Star-studded support: Heidi Klum, Leona Lewis and George Clooney Stand Up To Cancer in charity telethon
00:04 GMT, 20 October 2012
Their lives may be full of wealth and privilege, but a number of the world's biggest stars decided to give something back on Friday night.
The likes of Heidi Klum, George Clooney, Samuel L Jackson and Leona Lewis dedicated their evening to Channel 4's Stand Up To Cancer charity telethon.
Flaunting her supermodel figure, Heidi put in an appearance on Alan Carr's Chatty Man show, showcasing a T-shirt she had designed specially in honour of the event.
Model behaviour: Heidi Klum appeared on the Stand Up To Cancer telethon wearing a T-shirt she had designed herself
Pucker up: The German supermodel treated host Alan Carr to a huge kiss
Strutting her stuff in a pair of form-fitting leather trousers, the German beauty looked simply stunning as she treated the host in question to a huge kiss on live television.
In addition to pledges from the likes of David Beckham, George Clooney, Kylie Minogue and Jennifer Aniston, a number of fun-loving stars took part in humorous sketches and game shows to raise more money for the cause.
Actors Max Beesley and Stephen Graham couldn't seem to stop hugging Davina McCall after they emerged victorious from Million Pound Drop, while comedians Leigh Francis and Jack Whitehall also gave the game a shot.
Flawless: Leona Lewis was one of the many performers for the evening
A-list crowd: George Clooney and Kylie Minogue were among the stars who made pledges throughout the course of the Channel 4 show
She's got The X Factor: Nicole Scherzinger appeared in a comedy skit at the start of the show
Olympic hero: Diving star Tom Daley was urging viewers to call and make a donation to the cause
Elsewhere, the likes of Formula One star Lewis Hamilton, Hollywood actor Samuel L Jackson, and fashion expert Gok Wan made appearances on Alan Carr's infamous chat show.
But newlyweds Dawn Porter and Chris O'Dowd opted for something decidedly out of the ordinary, with the Bridesmaid actor 'shooting' his wife all in the name of charity.
Assisted by illusionist Derren Brown, the star performed the stunt using a paintball, having to pick from five different guns in the hope of choosing the loaded weapon.
Bringing it all together: (L-R) Alan Carr, Davina McCall and Dr Christian Jensen hosted the Channel 4 show
Doing their bit: David Beckham and Jennifer Aniston put in appearances on the charity telethon
Vrooom: Lewis Hamilton appeared on Alan Carr's Chatty Man Show
Dawn later wrote on her Twitter page: 'Good night everyone. What a brilliant thing to be a part of. I have donated, I hope you have too. Standing Up Tp Cancer is vital #donate.'
Hosted by Davina McCall, Dr Christian Jensen and Alan Carr, performances came from the likes of Leona Lewis and Cheryl Cole.
But while the Bleeding Love hitmaker's stage time was as flawless as ever, Cheryl suffered the embarrassment of mic problems at the start of her rendition of Call My Name.
His Heart Skipped A Beat: Olly Murs was left terrified after thinking JLS hunk Aston Merrygold had been injured in a human cannonball accident
Newlyweds: Dawn Porter and Chris O'Dowd were part of a Derren Brown experiment, which saw the Bridesmaids actor 'shoot' his new wife
Meanwhile, Olly Murs was also left red-faced, after he was pranked by JLS into thinking Aston Merrygold was severely injured after being shot out of a human cannonball.
And the laughs continued with the Made In Chelsea cast, who swapped the King's Road for their local checkout, bagging jobs at a local branch of Tesco.
To donate, visit http://su2c.channel4.com/
or call 0300 123 4444. Find SU2C on Facebook or Twitter.
Hollywood's finest: Samuel L Jackson also appeared on Alan Carr's sofa
Jumping for joy: Max Beesley and Stephen Graham couldn't seem to stop hugging Davina McCall after they emerged victorious from Million Pound Drop
Sound issues: Cheryl Cole's performance didn't go entirely according to plan